Ecthyma gangrenosum is a necrotic skin lesion that is often a sign of serious systemic infection. This lesion is most commonly caused by the bacterium Pseudomonas aeruginosa. The lesion initially appears as a papule or vesicle that quickly enlarges into a bulla, rapidly developing into a necrotic ulcer with purplish or blackish edges. This condition is common in patients with impaired immunity, such as cancer patients, HIV-positive individuals, or patients in intensive care units. Rapid diagnosis through clinical examination, Gram staining, and culture is crucial to prevent sepsis. Immediate treatment with antipseudomonas antibiotics can save the patient’s life.
